Publications

Alejandro J. Cortese, Conrad L. Smart, Tianyu Wang, Michael F. Reynolds, Samantha L. Norris, Yanxin Ji, Sunwoo Lee, Aaron Mok, Chunyan Wu, Fei Xia, Nathan I. Ellis, Alyosha C. Molnar, Chris Xu, and Paul L. McEuen
“Microscopic sensors using optical wireless integrated circuits”, PNAS, April 17, 2020

Priya S. Balasubramanian, Ankur Singh, ChrisXu, and Amit Lal
“GHz Ultrasonic Chip-Scale Device Induces Ion Channel Stimulation in Human Neural Cells”, Scientific Reports | (2020) 10:3075

Tianyu Wang, Chunyan Wu, Dimitre G Ouzounov, Wenchao Gu, Fei Xia, Minsu Kim, Xusan Yang, Melissa R Warden, and Chris Xu
“Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain”, eLife 2020; 9: e53205 DOI: 10.7554/eLife.53205

Bo Li, Chunyan Wu, Mengran Wang, Kriti Charan, and Chris Xu
“An adaptive excitation source for high-speed multiphoton microscopy“, Nature Methods 17, 163–166 (2020), doi:10.1038/s41592-019-0663-9

Dimitre G Ouzounov, Tianyu Wang, Chunyan Wu, and Chris Xu
“GCaMP6 ΔF/F dependence on the excitation wavelength in 3-photon and 2-photon microscopy of mouse brain activity”, Biomedical Optics Express Vol. 10, Issue 7, pp. 3343-3352 (2019)>>> Link

Mengran Wang, Minsu Kim, Fei Xia, and Chris Xu
“Impact of the emission wavelengths on in vivo multiphoton imaging of mouse brains”, Biomedical Optics Express Vol. 10, Issue 4, pp. 1905-1918 (2019)>>> Link

Qin, Q., Li, B., Xia, F., Xia, Y., and Xu, C.
“Multi-color background-free coherent anti-Stokes Raman scattering microscopy using a time-lens source“, Opt. Express 26(26), 34474-34483 (2018)  >>> Link

Fei Xia, Chunyan Wu, David Sinefeld, Bo Li, Yifan Qin, and Chris Xu
“In vivo label-free confocal imaging of the deep mouse brain with long-wavelength illumination“, Biomed. Opt. Exp.,  Vol. 9, Issue 12, pp. 6545-6555, (2018) >>> Link

Zhangyuanzhu Liu, Xiaobei Luo, Wei Jiang, Dexin Chen, Weisheng Chen, Kai Li, Xiumin Liu, Ziming Cui, Zhiming Li, Zelong Han, Side Liu, Guoxin Li, Chris Xu, Jun Yan
“Real-time in vivo optical biopsy using confocal laser endomicroscopy to evaluate distal margin in situ and determine surgical procedure in low rectal cancer”, Surgical Endoscopy https://doi.org/10.1007/s00464-018-6519-z (2018) >>> Link

Jun Yan, Xiaoling Zheng, Zhangyuanzhu Liu, Wenju Liu, Dajia Lin, Dexin Chen, Kai Li, Wei Jiang, Zhiming Li, Ning Zuo, Gang Chen, Jianping Lu, Jianxin Chen, Guoxin Li, Chris Xu, Shuangmu Zhuo
“Multiphoton imaging provides a superior optical biopsy to that of confocal laser endomicroscopy imaging for colorectal lesions”, Endoscopy DOI: 10.1055/a-0641-5091, (2018) >>> Link

Feng‐Chieh Li, Sheng‐Lin Lee, Hung‐Ming Lin, Chih‐Ju Lin, Sheng‐Shun Wang, Yu‐Yuan Lee, Su‐Yen Lo, Tzu‐Lin Sun, Wei‐Liang Chen, Wen Lo, Nicholas Horton, Chris Xu, Shu‐Jen Chiang, Yang‐Fang Chen, Hsuan‐Shu Lee, Chen‐Yuan Dong
“Dynamic visualization of the recovery of mouse hepatobiliary metabolism to acetaminophen‐overdose damage”, J. Biophoton, e201800296, (2018) >>> Link

T. Wang, D. G. Ouzounov, C. Wu, N. G. Horton, B. Zhang, C. Wu, Y. Zhang, M. J. Schnitzer, and C. Xu
“Three-photon imaging of mouse brain structure and function through the intact skull”, Nature Methods 15, pages789–792 (2018) >>> Link

B. Li, M. Wang, K. Charan, M. Li, and C. Xu
“Investigation of the long wavelength limit of soliton self-frequency shift in a silica fiber”, Opt. Exp., 26, pp. 19637-19647(2018) >>> Link

M. Wang, C. Wu, D. Sinefeld, B. Li, F. Xia, and C. Xu
“Comparing the effective attenuation lengths for long wavelength in vivo imaging of the mouse brain”, Biomed. Opt. Exp., 9, 3534-3543, (2018) >>> Link

K. Charan, B. Li, M. Wang, C. Lin, and C. Xu
“Fiber-based, tunable repetition rate source for deep tissue two-photon fluorescence microscopy”, Biomed. Opt. Exp., 9, 2304-2311, (2018) >>> Link

Bingying Chen, Xiaoshuai Huang, Dongzhou Gou, Jianzhi Zeng, Guoqing Chen, Meijun Pang, Yanhui Hu, Zhe Zhao, Yunfeng Zhang, Zhuan Zhou, Haitao Wu, Heping Cheng, Zhigang Zhang, Chris Xu, Yulong Li, Liangyi Chen, and Aimin Wang
“Rapid volumetric imaging with Bessel-Beam three-photon microscopy”, Biomed. Opt. Exp., 9, 1992-2000, (2018) >>> Link

W. Liu, Y. Zhou, M. Wang, L. Li, E. Vienneau, R. Chen, J. Luo, C. Xu, Q. Zhou, L. V. Wang, and J. Yao
“Correcting the limited view in optical-resolution photoacoustic microscopy”, J. Biophoton, (2018) >>> Link

F. Xia, D. Sinefeld, B. Li and C. Xu
“Two-photon Shack–Hartmann wavefront sensor”, Opt. Lett. Vol. 42, Issue 6, pp. 1141-1144 (2017) >>> Link

D. Ouzounov, T. Wang, M. Wang, D. Feng, N. Horton, J. Cruz-Hernández, Y. Cheng, J. Reimer, A. Tolias, N. Nishimura and C. Xu
“In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain”, Nature Methods 14, 388–390, (2017) doi:10.1038/nmeth.4183 >>> Link

G. Rasskazov, A. Ryabtsev, K. Charan, T. Wang, C. Xu, and M. Dantus
“Characterization and adaptive compression of a multi-soliton laser source”, Opt. Exp., Vol. 25, Issue 1, pp. 320-329 (2017) >>> Link

B. Li, K. Charan, K. Wang, T. Rojo, D. Sinefeld, and C. Xu
“Nonresonant background suppression for coherent anti-Stokes Raman scattering microscopy using a multi-wavelength timelens source”, Opt. Exp., 24, 26687, 2016 >>> Link

C. Lin, F. Li, Y. Lee, T. Tseng, W. Chen, V. Hovhannisyan, N. Kang, N. G. Horton, S. Chiang, C. Xu, H. Lee, and C. Dong
“Direct visualization of functional heterogeneity in hepatobiliary metabolism using 6-CFDA as model compound”, Biomed. Opt. Exp., 7, 3574, 2016 >>> Link

Yuxing Tang, Logan G. Wright, Kriti Charan, Tianyu Wang, Chris Xu, and Frank W. Wise
“Generation of intense 100  fs solitons tunable from 2 to 4.3  μm in fluoride fiber“, Optica 3(9), 948-951, 2016 >>> Link

H. S. Wei, H. Kang, I. D. Rasheed, S. Zhou, N. Lou, A. Gershteyn, E. D. McConnell, Y. Wang, K. E. Richardson, A. F. Palmer, C. Xu, J. Wan, M. Nedergaard
“Erythrocytes are oxygen-sensing regulators of the cerebral microcirculation“, Neuron, 91, 851–862, 2016 >>> Link

D. Sinefeld, H. P. Paudel, D. G. Ouzounov, T. G. Bifano, and C. Xu
“Adaptive optics in multiphoton microscopy: comparison of two, three and four photon fluorescence“, Optics Express., Vol. 23, Issue 24, pp. 31472-31483, 2015.  >>> Link

N. G. Horton and C. Xu
“Dispersion compensation in three-photon fluorescence microscopy at 1,700 nm“, Biomedical Optics Express 6(4), 1392–1397 (2015) >>> Link

Luke J. Mortensen, Clemens Alt, Raphaël Turcotte, Marissa Masek, Tzu-Ming Liu, Daniel C. Côté, Chris Xu, Giuseppe Intini, and Charles P. Lin
“Femtosecond laser bone ablation with a high repetition rate fiber laser source”  Biomedical Optics Express, Vol. 6, Issue 1, pp. 32-42 (2015) >>> Link

D. M. Huland, M. Jain, D. G. Ouzounov, B. D. Robinson, D. S. Harya, M. M. Shevchuk, P. Singhal, C. Xu, A. K. Tewari
“Multiphoton gradient index endoscopy for evaluation of diseased human prostatic tissue ex vivo”  J. Biomed. Opt., Vol. 19, Iss. 11, pp. 116011, 2014. >>> Link

L. Cheng, N. G. Horton, K. Wang, S. Chen, and C. Xu
“Measurements of multiphoton action cross sections for multiphoton microscopy”  Biomed. Opt. Exp., Vol. 5, Iss. 10, pp. 3427–3533, 2014. >>> Link

L. Cheng, C. Lien, Y. Sie, Y. Hu, C. Lin, F. Chien, C. Xu, C. Dong, and S. Chen
“Nonlinear structured-illumination enhanced temporal focusing multiphoton excitation microscopy with a digital micromirror device”  Biomed. Opt. Exp., Vol. 5, Iss. 8, pp. 2526–2536, 2014. >>> Link

C. Chang, L. Cheng, H. Su, Y. Hu, K. Cho, W. Yen, C. Xu, C. Dong, and S. Chen
“Wavefront sensorless adaptive optics temporal focusing-based multiphoton microscopy”  Biomed. Opt. Exp., Vol. 5, Iss. 6, pp. 1768–1777, 2014. >>> Link

K. Wang, N. G. Horton, K. Charan, and C. Xu
“Advanced fiber soliton sources for nonlinear deep tissue imaging in biophotonics”  IEEE J. Sel. Topics in Quantum Elec., 20, 6800311, 2014. >>> Link

K. Charan, M. E. V. Pedersen, K. Wang, L. Grüner-Nielsen, D. Jakobsen, C. Xu
“Experimental demonstration of soliton cascade in higher-order-mode fibers”  IEEE Photonics Technology Letters, 26, 301-304, 2014. >>> Link