Welcome to Chris Xu Group
Our research has two main thrusts: biomedical imaging and fiber optics. We are exploring new concepts and techniques for in vivo imaging deep into scattering biological specimens, such as mouse brain. We are developing new medical endoscopes for non-invasive real-time diagnostics of tissues without any exogenous contrast agent. We are developing novel optical fibers and fiber-based devices for biomedical imaging and optical communications. Learn more about our research.
Latest News
Intravital imaging of mouse lymph nodes, Nature Immunology (01/2022)
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Imaging Drosophila through the intact cuticle, eLife (01/2022)
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Intravital imaging the subventricular zone, Cerebral Cortex (01/2022).
Intravital imaging the...
Multi-color deep imaging, Science Advances (03/17/2021).
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SPIE Luminary: Chris Xu (02/05/2021)
With this series, SPIE celebrates...
Watch Chris’s 10-minute talk on in vivo three-photon imaging of mouse brain
Chris’s 10-minute talk on...
Interview with Chris Xu after his plenary talk at CLEO
Neural Imaging: Deeper, Faster,...
Review paper on three-photon imaging is published in Optica (08/11/2020).
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Latest Publications
Neurophotonic tools for microscopic measurements and manipulation: status report
Neurophotonic tools for...
Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes
Kibaek Choe, Yusaku Hontani,...
Multiphoton imaging of neural structure and activity in Drosophila through the intact cuticle
Max Jameson Aragon, Aaron T Mok,...
Intravital imaging the subventricular zone with three photon microscopy
Bin Sun, Mengran Wang, Anna...
Deep-tissue Three-photon Fluorescence Microscopy in Intact Mouse and Zebrafish Brain
Hontani, Y., Akbari, N., Kolkman,...
Imaging deeper than the transport mean free path with multiphoton microscopy
Najva Akbari, Mihailo R Rebec,...
Latest Patents
Dual Mode Microendoscope Apparatus, Method and Applications
Dimitre Ouzonouv, Watt W. Webb,...
Dynamic Measurement of and Compensation for Impairments to Optical Data Communication Pulses Using Photon-Counting Silicon Avalanche Photodiode
Knox, W. H., J. M. Roth, and C....
Method, Apparatus and System for Reducing Gain Ripple in a Raman-Amplified Wdm System
Fishman, D.A., S. Hunsche, X....
Optical Device for Generating Pulsed Light
Dinu, M., C. Kerbage, X. Liu, F....
Process for Fabricating Tapered Microstructured Fiber System and Resultant System
Chandalia, J., D.J. DiGiovanni,...