Welcome to Chris Xu Group
Our research has two main thrusts: biomedical imaging and fiber optics. We are exploring new concepts and techniques for in vivo imaging deep into scattering biological specimens, such as mouse brain. We are developing new medical endoscopes for non-invasive real-time diagnostics of tissues without any exogenous contrast agent. We are developing novel optical fibers and fiber-based devices for biomedical imaging and optical communications. Learn more about our research.


Latest News
Multi-color 3-photon deep imaging with enhanced cross sections is published in Science Advances (03/17/2021).
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SPIE Luminary: Chris Xu (02/05/2021)
With this series, SPIE celebrates...
Review paper on three-photon imaging is published in Optica (08/11/2020).
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Chris Xu is the new holder of the IBM Professorship of Engineering, a prestigious endowed chair (07/01/2020).
Deep three-photon imaging of the brain in intact adult zebrafish is published in Nature Methods (04/27/2020).
Dawnis M. Chow, David Sinefeld,...
Watch Chris’s 10-minute talk on in vivo three-photon imaging of mouse brain
Chris’s 10-minute talk on...
Chris Xu delivered a plenary talk at CLEO 2019
Neural Imaging: Deeper, Faster,...
Latest Publications
Multicolor three-photon fluorescence imaging with single-wavelength excitation deep in mouse brain
Yusaku Hontani, Fei Xia, and...
Three-photon neuronal imaging in deep mouse brain
Tianyu Wang and Chris Xu...
Deep three-photon imaging of the brain in intact adult zebrafish
Dawnis M. Chow, David Sinefeld,...
Microscopic sensors using optical wireless integrated circuits
Alejandro J. Cortese, Conrad L....
GHz Ultrasonic Chip-Scale Device Induces Ion Channel Stimulation in Human Neural Cells
Priya S. Balasubramanian, Ankur...
Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain
Tianyu Wang, Chunyan Wu, Dimitre...
Latest Patents
Dynamic Measurement of and Compensation for Impairments to Optical Data Communication Pulses Using Photon-Counting Silicon Avalanche Photodiode
Knox, W. H., J. M. Roth, and C....
Method, Apparatus and System for Reducing Gain Ripple in a Raman-Amplified Wdm System
Fishman, D.A., S. Hunsche, X....
Optical Device for Generating Pulsed Light
Dinu, M., C. Kerbage, X. Liu, F....
Process for Fabricating Tapered Microstructured Fiber System and Resultant System
Chandalia, J., D.J. DiGiovanni,...
Ultra-Fast Probe
Xu, C., and W. H. Knox....