Welcome to Chris Xu Group
Our research has two main thrusts: biomedical imaging and fiber optics. We are exploring new concept and techniques, including novel ultrafast lasers and fiber optics, adaptive optics, and computation/ML, for imaging deep and fast.
Learn more about our research.
Latest News
Shitong Zhao won the best Poster award at Photonics West 2026! Congrats!
Shitong Zhao won the best Poster...
OPN article on Deep Multiphoton Imaging (04/2025)
OPN article on deep multiphoton...
Large FOV 2- and 3-photon imaging is published in eLight (2024)
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Review on “Multiphoton fluorescence microscopy for in vivo imaging” published in Cell (2024)
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New K99/R00 grant awarded to postdoc Xi Chen. Congrats! (02/2023)
Xi Chen won an NIH Pathway to...
Watch Chris’s 10-minute talk on in vivo three-photon imaging of mouse brain
Chris’s 10-minute talk on...
Interview with Chris Xu after his plenary talk at CLEO
Neural Imaging: Deeper, Faster,...
Intravital imaging of mouse lymph nodes, Nature Immunology (01/2022)
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Latest Publications
Systematic analysis of immune cell motility leveraging the open intravital microscopy database Immunemap
Systematic analysis of immune...
A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice
Sunwoo Lee, Shahaboddin Ghajari,...
Efficient Raman shifting of microjoule pulses in N2-filled anti-resonant fiber
Yishai Eisenberg, Yi-Hao Chen,...
Functional connectomics spanning multiple areas of mouse visual cortex
The MICrONS Consortium,...
Label-Free Multiphoton Imaging Reveals Volumetric Shifts Across Development in Sensory-Related Brain Regions of a Miniature Transparent Vertebrate
Rose L. Tatarsky, Najva...
Multi-megawatt pulses from 1030 to 1300 nm based on soliton self-frequency shifting in a nitrogen-filled fiber
Yishai Eisenberg, Wenchao Wang,...
Latest Patents
GHz-THz ultrasonics and optics for neurotechnology devices, methods, and applications
US Patent No. 12319567 GHz-THz...
Adaptive illumination apparatus, method, and applications
Chris Xu, Kriti Charan, Bo Li...
Dual Mode Microendoscope Apparatus, Method and Applications
Dimitre Ouzonouv, Watt W. Webb,...
Multi-focal optical component, optical system, and imaging method
US Patent 9,375,136 Multi-focal...
Optical mode conversion by nonlinear effects
US Patent 9,482,817 Optical mode...
Fiber designs for wavelength tunable ultra-short pulse lasers
US Patent 9,502,852 Fiber designs...