Welcome to Chris Xu Group
Our research has two main thrusts: biomedical imaging and fiber optics. We are exploring new concept and techniques, including novel ultrafast lasers and fiber optics, adaptive optics, and computation/ML, for imaging deep and fast.
Learn more about our research.
Latest News
Review paper on three-photon imaging is published in Optica (08/11/2020).
...
Three new papers published. Two on multiphoton imaging depth limit and the third on measurements of optical transmission of various tissues (12/2021).
Multiphoton imaging depth limit:...
Chris Xu is the new holder of the IBM Professorship of Engineering, a prestigious endowed chair (07/01/2020).
Deep three-photon imaging of the brain in intact adult zebrafish is published in Nature Methods (04/27/2020).
Dawnis M. Chow, David Sinefeld,...
Quantitative analysis of three-photon calcium imaging is published in eLife (01/30/2020)
Tianyu Wang, Chunyan Wu, Dimitre...
New adaptive excitation source for multiphoton imaging is published in Nature Methods (12/02/2019)
An adaptive excitation source for...
Three-photon imaging of mouse brain structure and function through the intact skull is published in Nature Methods (09/10/2018)
Three-photon imaging of mouse...
Live-cell imaging: Deeper, faster, wider (03/30/2018)
TECHNOLOGY FEATURE / Science...
Latest Publications
Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes
Kibaek Choe, Yusaku Hontani,...
Multiphoton imaging of neural structure and activity in Drosophila through the intact cuticle
Max Jameson Aragon, Aaron T Mok,...
Intravital imaging the subventricular zone with three photon microscopy
Bin Sun, Mengran Wang, Anna...
Deep-tissue Three-photon Fluorescence Microscopy in Intact Mouse and Zebrafish Brain
Hontani, Y., Akbari, N., Kolkman,...
Imaging deeper than the transport mean free path with multiphoton microscopy
Najva Akbari, Mihailo R Rebec,...
Spatially resolved measurements of ballistic and total transmission in microscale tissue samples from 450 nm to 1624 nm
Aaron T. Mok, Jamien Shea,...
Latest Patents
Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods
US Patent 8,705,184 Multi-path,...
Producing Optical Pulses of a Desired Wavelength Using Cherenkov Radiation
US 8,556,824 Producing Optical...
Production of Optical Pulses at a Desired Wavelengt Using Soliton Self-Frequency Shift in Higher Order Mode Fiber
US 8,554,035 Production of...
Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods
US 8,553,337 Multi-path,...
Methods and systems for compensation of self-phase modulation in fiber-based amplification systems
US 8,102,594 Methods and systems...
All-optical, continuously tunable, pulse delay generator using wavelength conversion and dispersion
US 7,538,935 All-optical,...